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In patients whose symptoms are refractory to rigorously implemented conservative therapy, the key surgical options are sacral neuromodulation, sphincteroplasty, some implantable biomaterials and, as a final resort, colonic stoma

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In such cases, Vitamin B12 shots offer a direct and efficient method of supplementation

Dihexa is a peptide variant derived from angiotensin IV which has been found to potently improve cognitive function in animal models of disease such as Alzheimers